Control of CXCR2 activity through its ubiquitination on K327 residue

BACKGROUND: The interleukin-8 chemokine (IL-8) G-protein coupled receptor CXCR2 governs pro-inflammatory and pro-angiogenic responses in leukocytes and endothelial cells. At a molecular standpoint, CXCR2 is widely reported to operate through calcium flux, phosphoinoisitide 3 kinase (PI3K) and mitoge...

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Detalles Bibliográficos
Autores principales: Leclair, Héloise M, Dubois, Sonia M, Azzi, Sandy, Dwyer, Julie, Bidère, Nicolas, Gavard, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209453/
https://www.ncbi.nlm.nih.gov/pubmed/25339290
http://dx.doi.org/10.1186/s12860-014-0038-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209453/
https://www.ncbi.nlm.nih.gov/pubmed/25339290
http://dx.doi.org/10.1186/s12860-014-0038-0

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