Cutting the brakes and flooring the gas: how TMEPAI turns TGF-β into a tumor promoter

In normal or nonmalignant cells, TGF-β inhibits cellular proliferation through activation of the SMAD-dependent canonical signaling pathway. Recent findings demonstrate that the protein TMEPAI1 can block the cytostatic effects of the canonical TGF-β signaling pathway, while activating cellular proli...

Descripción completa

Detalles Bibliográficos
Autores principales: Cichon, Magdalena A., Radisky, Derek C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209605/
https://www.ncbi.nlm.nih.gov/pubmed/25352947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209605/
https://www.ncbi.nlm.nih.gov/pubmed/25352947

Ejemplares similares