Aberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing loss

Mutation of the GJB2 gene, which encodes the connexin 26 (Cx26) gap junction (GJ) protein, is the most common cause of hereditary, sensorineural hearing loss. Cx26 is not expressed in hair cells, but is widely expressed throughout the non-sensory epithelial cells of the cochlea. Most GJB2 mutations...

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Detalles Bibliográficos
Autores principales: Sanchez, Helmuth A., Verselis, Vytas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209889/
https://www.ncbi.nlm.nih.gov/pubmed/25386120
http://dx.doi.org/10.3389/fncel.2014.00354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209889/
https://www.ncbi.nlm.nih.gov/pubmed/25386120
http://dx.doi.org/10.3389/fncel.2014.00354

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