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PICK1 links Argonaute 2 to endosomes in neuronal dendrites and regulates miRNA activity
MicroRNAs fine-tune gene expression by inhibiting the translation of mRNA targets. Argonaute (Ago) proteins are critical mediators of microRNA-induced post-transcriptional silencing and have been shown to associate with endosomal compartments, but the molecular mechanisms that underlie this process...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210090/ https://www.ncbi.nlm.nih.gov/pubmed/24723684 http://dx.doi.org/10.1002/embr.201337631 |