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Positive Allostery in Metal Ion Binding by a Cooperatively Folded β-Peptide Bundle

[Image: see text] Metal ion binding is exploited by proteins in nature to catalyze reactions, bind molecules, and favor discrete structures, but it has not been demonstrated in β-peptides or their assemblies. Here we report the design, synthesis, and characterization of a β-peptide bundle that uniqu...

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Detalles Bibliográficos
Autores principales: Miller, Jonathan P., Melicher, Michael S., Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210112/
https://www.ncbi.nlm.nih.gov/pubmed/25290247
http://dx.doi.org/10.1021/ja508872q