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A Boronate-Caged [(18)F]FLT Probe for Hydrogen Peroxide Detection Using Positron Emission Tomography

[Image: see text] Reactive oxygen species (ROS) play important roles in the development and progression of cancer and other diseases, motivating the development of translatable technologies for biological ROS imaging. Here we report Peroxy-Caged-[(18)F]Fluorodeoxy thymidine-1 (PC-FLT-1), an oxidativ...

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Detalles Bibliográficos
Autores principales: Carroll, Valerie, Michel, Brian W., Blecha, Joseph, VanBrocklin, Henry, Keshari, Kayvan, Wilson, David, Chang, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210116/
https://www.ncbi.nlm.nih.gov/pubmed/25310369
http://dx.doi.org/10.1021/ja509198w