Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction

[Image: see text] Penicillin-binding proteins (PBPs) are involved in the synthesis and remodeling of bacterial peptidoglycan (PG). Staphylococcus aureus expresses four PBPs. Genetic studies in S. aureus have implicated PBP4 in the formation of highly cross-linked PG, but biochemical studies have not...

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Detalles Bibliográficos
Autores principales: Qiao, Yuan, Lebar, Matthew D., Schirner, Kathrin, Schaefer, Kaitlin, Tsukamoto, Hirokazu, Kahne, Daniel, Walker, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210121/
https://www.ncbi.nlm.nih.gov/pubmed/25291014
http://dx.doi.org/10.1021/ja508147s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210121/
https://www.ncbi.nlm.nih.gov/pubmed/25291014
http://dx.doi.org/10.1021/ja508147s

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