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Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971

[Image: see text] The imaging of translocator 18 kDa protein (TSPO) in living human brain with radioligands by positron emission tomography (PET) has become an important means for the study of neuroinflammatory conditions occurring in several neuropsychiatric disorders. The widely used prototypical...

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Detalles Bibliográficos
Autores principales: Zanotti-Fregonara, Paolo, Zhang, Yi, Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Sbardella, Gianluca, Castellano, Sabrina, Taliani, Sabrina, Martini, Claudia, Innis, Robert B., Da Settimo, Federico, Pike, Victor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210126/
https://www.ncbi.nlm.nih.gov/pubmed/25123416
http://dx.doi.org/10.1021/cn500138n