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A Breast Cancer Stem Cell-Selective, Mammospheres-Potent Osmium(VI) Nitrido Complex

[Image: see text] The effect of a newly developed osmium(VI) nitrido complex, 1, on breast cancer stem cells (CSCs) is reported. The complex displays selective toxicity for HMLER breast cancer cells enriched with CD44-positive, CSC-like cells over the same cells having reduced CSC character. Remarka...

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Detalles Bibliográficos
Autores principales: Suntharalingam, Kogularamanan, Lin, Wei, Johnstone, Timothy C., Bruno, Peter M., Zheng, Yao-Rong, Hemann, Michael T., Lippard, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210142/
https://www.ncbi.nlm.nih.gov/pubmed/25247635
http://dx.doi.org/10.1021/ja508808v