Probing the Rate-Limiting Step for Intramolecular Transfer of a Transcription Factor between Specific Sites on the Same DNA Molecule by (15)N(z)-Exchange NMR Spectroscopy

[Image: see text] The kinetics of translocation of the homeodomain transcription factor HoxD9 between specific sites of the same or opposite polarities on the same DNA molecule have been studied by (15)N(z)-exchange NMR spectroscopy. We show that exchange occurs by two facilitated diffusion mechanis...

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Detalles Bibliográficos
Autores principales: Ryu, Kyoung-Seok, Tugarinov, Vitali, Clore, G. Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210153/
https://www.ncbi.nlm.nih.gov/pubmed/25253516
http://dx.doi.org/10.1021/ja5081585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210153/
https://www.ncbi.nlm.nih.gov/pubmed/25253516
http://dx.doi.org/10.1021/ja5081585

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