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Probing the Rate-Limiting Step for Intramolecular Transfer of a Transcription Factor between Specific Sites on the Same DNA Molecule by (15)N(z)-Exchange NMR Spectroscopy
[Image: see text] The kinetics of translocation of the homeodomain transcription factor HoxD9 between specific sites of the same or opposite polarities on the same DNA molecule have been studied by (15)N(z)-exchange NMR spectroscopy. We show that exchange occurs by two facilitated diffusion mechanis...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210153/ https://www.ncbi.nlm.nih.gov/pubmed/25253516 http://dx.doi.org/10.1021/ja5081585 |