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Acute, Delayed and Chronic Remote Ischemic Conditioning Is Associated with Downregulation of mTOR and Enhanced Autophagy Signaling

BACKGROUND: Remote ischemic conditioning (RIC), induced by brief periods of limb ischemia has been shown to decrease acute myocardial injury and chronic responses after acute coronary syndromes. While several signaling pathways have been implicated, our understanding of the cardioprotection and its...

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Detalles Bibliográficos
Autores principales: Rohailla, Sagar, Clarizia, Nadia, Sourour, Michel, Sourour, Wesam, Gelber, Nitai, Wei, Can, Li, Jing, Redington, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210174/
https://www.ncbi.nlm.nih.gov/pubmed/25347774
http://dx.doi.org/10.1371/journal.pone.0111291