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Expression of Truncated PITX3 in the Developing Lens Leads to Microphthalmia and Aphakia in Mice
Microphthalmia is a severe ocular disorder, and this condition is typically caused by mutations in transcription factors that are involved in eye development. Mice carrying mutations in these transcription factors would be useful tools for defining the mechanisms underlying developmental eye disorde...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210183/ https://www.ncbi.nlm.nih.gov/pubmed/25347445 http://dx.doi.org/10.1371/journal.pone.0111432 |