Expression of Truncated PITX3 in the Developing Lens Leads to Microphthalmia and Aphakia in Mice

Microphthalmia is a severe ocular disorder, and this condition is typically caused by mutations in transcription factors that are involved in eye development. Mice carrying mutations in these transcription factors would be useful tools for defining the mechanisms underlying developmental eye disorde...

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Detalles Bibliográficos
Autores principales: Wada, Kenta, Matsushima, Yoshibumi, Tada, Tomoki, Hasegawa, Sayaka, Obara, Yo, Yoshizawa, Yasuhiro, Takahashi, Gou, Hiai, Hiroshi, Shimanuki, Midori, Suzuki, Sari, Saitou, Junichi, Yamamoto, Naoki, Ichikawa, Masumi, Watanabe, Kei, Kikkawa, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210183/
https://www.ncbi.nlm.nih.gov/pubmed/25347445
http://dx.doi.org/10.1371/journal.pone.0111432

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