Structural and Functional Characterization of Cleavage and Inactivation of Human Serine Protease Inhibitors by the Bacterial SPATE Protease EspPα from Enterohemorrhagic E. coli

EspPα and EspI are serine protease autotransporters found in enterohemorrhagic Escherichia coli. They both belong to the SPATE autotransporter family and are believed to contribute to pathogenicity via proteolytic cleavage and inactivation of different key host proteins during infection. Here, we de...

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Detalles Bibliográficos
Autores principales: Weiss, André, Joerss, Hanna, Brockmeyer, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210187/
https://www.ncbi.nlm.nih.gov/pubmed/25347319
http://dx.doi.org/10.1371/journal.pone.0111363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210187/
https://www.ncbi.nlm.nih.gov/pubmed/25347319
http://dx.doi.org/10.1371/journal.pone.0111363

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