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A Novel In Vitro Method for Detecting Undifferentiated Human Pluripotent Stem Cells as Impurities in Cell Therapy Products Using a Highly Efficient Culture System

Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated with tumorigencity. However, no simple in vitro me...

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Detalles Bibliográficos
Autores principales: Tano, Keiko, Yasuda, Satoshi, Kuroda, Takuya, Saito, Hirohisa, Umezawa, Akihiro, Sato, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210199/
https://www.ncbi.nlm.nih.gov/pubmed/25347300
http://dx.doi.org/10.1371/journal.pone.0110496