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Prenatal Polycyclic Aromatic Hydrocarbon, Adiposity, Peroxisome Proliferator-Activated Receptor (PPAR) γ Methylation in Offspring, Grand-Offspring Mice

RATIONALE: Greater levels of prenatal exposure to polycyclic aromatic hydrocarbon (PAH) have been associated with childhood obesity in epidemiological studies. However, the underlying mechanisms are unclear. OBJECTIVES: We hypothesized that prenatal PAH over-exposure during gestation would lead to w...

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Detalles Bibliográficos
Autores principales: Yan, Zhonghai, Zhang, Hanjie, Maher, Christina, Arteaga-Solis, Emilio, Champagne, Frances A., Wu, Licheng, McDonald, Jacob D., Yan, Beizhan, Schwartz, Gary J., Miller, Rachel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210202/
https://www.ncbi.nlm.nih.gov/pubmed/25347678
http://dx.doi.org/10.1371/journal.pone.0110706