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The Nuclear IκB Family Protein IκB(NS) Influences the Susceptibility to Experimental Autoimmune Encephalomyelitis in a Murine Model

The nuclear IκB family protein IκB(NS) is expressed in T cells and plays an important role in Interferon (IFN)-γ and Interleukin (IL)-2 production. IκB-ζ, the most similar homolog of IκB(NS), plays an important role in the generation of T helper (Th)17 cells in cooperation with RORγt, a master regul...

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Detalles Bibliográficos
Autores principales: Kobayashi, Shuhei, Hara, Akira, Isagawa, Takayuki, Manabe, Ichiro, Takeda, Kiyoshi, MaruYama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210207/
https://www.ncbi.nlm.nih.gov/pubmed/25347393
http://dx.doi.org/10.1371/journal.pone.0110838