Systemically Administered IgG Anti-Toxin Antibodies Protect the Colonic Mucosa during Infection with Clostridium difficile in the Piglet Model

The use of anti-toxin human monoclonal antibodies (HMab) as treatment for C. difficile infection has been investigated in animal models and human clinical trials as an alternative to or in combination with traditional antibiotic therapy. While HMab therapy appears to be a promising option, how syste...

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Detalles Bibliográficos
Autores principales: Cohen, Ocean R., Steele, Jennifer A., Zhang, Quanshun, Schmidt, Diane J., Wang, Yuankai, Hamel, Philip E. S., Beamer, Gillian, Xu, Bingling, Tzipori, Saul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210241/
https://www.ncbi.nlm.nih.gov/pubmed/25347821
http://dx.doi.org/10.1371/journal.pone.0111075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210241/
https://www.ncbi.nlm.nih.gov/pubmed/25347821
http://dx.doi.org/10.1371/journal.pone.0111075

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