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A self-consistent approach for determining pairwise interactions that underlie channel activation

Signaling proteins such as ion channels largely exist in two functional forms, corresponding to the active and resting states, connected by multiple intermediates. Multiparametric kinetic models based on sophisticated electrophysiological experiments have been devised to identify molecular interacti...

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Detalles Bibliográficos
Autores principales: Chowdhury, Sandipan, Haehnel, Benjamin M., Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210424/
https://www.ncbi.nlm.nih.gov/pubmed/25311637
http://dx.doi.org/10.1085/jgp.201411184