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Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels
Voltage-dependent potassium channels play a crucial role in electrical excitability and cellular signaling by regulating potassium ion flux across membranes. Movement of charged residues in the voltage-sensing domain leads to a series of conformational changes that culminate in channel opening in re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210428/ https://www.ncbi.nlm.nih.gov/pubmed/25311635 http://dx.doi.org/10.1085/jgp.201411185 |