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Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels

Voltage-dependent potassium channels play a crucial role in electrical excitability and cellular signaling by regulating potassium ion flux across membranes. Movement of charged residues in the voltage-sensing domain leads to a series of conformational changes that culminate in channel opening in re...

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Detalles Bibliográficos
Autores principales: Chowdhury, Sandipan, Haehnel, Benjamin M., Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210428/
https://www.ncbi.nlm.nih.gov/pubmed/25311635
http://dx.doi.org/10.1085/jgp.201411185