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Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

Organogenesis and tumor metastasis involve the transformation of epithelia to highly motile mesenchymal-like cells. Septins are filamentous G proteins, which are overexpressed in metastatic carcinomas, but their functions in epithelial motility are unknown. Here, we show that a novel network of sept...

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Detalles Bibliográficos
Autores principales: Dolat, Lee, Hunyara, John L., Bowen, Jonathan R., Karasmanis, Eva Pauline, Elgawly, Maha, Galkin, Vitold E., Spiliotis, Elias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210437/
https://www.ncbi.nlm.nih.gov/pubmed/25349260
http://dx.doi.org/10.1083/jcb.201405050