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Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility
Organogenesis and tumor metastasis involve the transformation of epithelia to highly motile mesenchymal-like cells. Septins are filamentous G proteins, which are overexpressed in metastatic carcinomas, but their functions in epithelial motility are unknown. Here, we show that a novel network of sept...
Autores principales: | Dolat, Lee, Hunyara, John L., Bowen, Jonathan R., Karasmanis, Eva Pauline, Elgawly, Maha, Galkin, Vitold E., Spiliotis, Elias T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210437/ https://www.ncbi.nlm.nih.gov/pubmed/25349260 http://dx.doi.org/10.1083/jcb.201405050 |
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