Cargando…

CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins

Mitochondrial function requires coordination of two genomes for protein biogenesis, efficient quality control mechanisms, and appropriate distribution of the organelles within the cell. How these mechanisms are integrated is currently not understood. Loss of the Clu1/CluA homologue (CLUH) gene led t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Jie, Schatton, Désirée, Martinelli, Paola, Hansen, Henriette, Pla-Martin, David, Barth, Esther, Becker, Christian, Altmueller, Janine, Frommolt, Peter, Sardiello, Marco, Rugarli, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210445/
https://www.ncbi.nlm.nih.gov/pubmed/25349259
http://dx.doi.org/10.1083/jcb.201403129