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Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly
Cilia are microtubule-based organelles that assemble via intraflagellar transport (IFT) and function as signaling hubs on eukaryotic cells. IFT relies on molecular motors and IFT complexes that mediate the contacts with ciliary cargo. To elucidate the architecture of the IFT-B complex, we reconstitu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210449/ https://www.ncbi.nlm.nih.gov/pubmed/25349261 http://dx.doi.org/10.1083/jcb.201408002 |