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Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly

Cilia are microtubule-based organelles that assemble via intraflagellar transport (IFT) and function as signaling hubs on eukaryotic cells. IFT relies on molecular motors and IFT complexes that mediate the contacts with ciliary cargo. To elucidate the architecture of the IFT-B complex, we reconstitu...

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Detalles Bibliográficos
Autores principales: Taschner, Michael, Kotsis, Fruzsina, Braeuer, Philipp, Kuehn, E. Wolfgang, Lorentzen, Esben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210449/
https://www.ncbi.nlm.nih.gov/pubmed/25349261
http://dx.doi.org/10.1083/jcb.201408002