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Myofiber HLA-DR expression is a distinctive biomarker for antisynthetase-associated myopathy

OBJECTIVES: To assess the value of major histocompatibility complex (MHC) class II antigen (HLA-DR) expression to distinguish anti-synthetase myopathy (ASM) from dermatomyositis (DM). METHODS: Muscle biopsies from patients with ASM (n = 33), DM without anti-synthetase antibodies (ASAb) (n = 17), and...

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Detalles Bibliográficos
Autores principales: Aouizerate, Jessie, De Antonio, Marie, Bassez, Guillaume, Gherardi, Romain K, Berenbaum, Francis, Guillevin, Loïc, Berezne, Alice, Valeyre, Dominique, Maisonobe, Thierry, Dubourg, Odile, Cosnes, Anne, Benveniste, Olivier, Authier, François Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210467/
https://www.ncbi.nlm.nih.gov/pubmed/25339355
http://dx.doi.org/10.1186/s40478-014-0154-2