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Effectiveness of lithium in subjects with treatment-resistant depression and suicide risk: results and lessons of an underpowered randomised clinical trial

BACKGROUND: As lithium treatment might be effective in reducing the risk of deliberate self-harm (DSH) in adult patients with unipolar affective disorders, we designed a pragmatic randomised trial to assess its efficacy in more than 200 patients with treatment-resistant depression. However, we rando...

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Detalles Bibliográficos
Autores principales: Girlanda, Francesca, Cipriani, Andrea, Agrimi, Emilia, Appino, Maria Grazia, Barichello, Andrea, Beneduce, Rossella, Bighelli, Irene, Bisoffi, Giulia, Bisogno, Alfredo, Bortolaso, Paola, Boso, Marianna, Calandra, Carmela, Cascone, Liliana, Castellazzi, Mariasole, Corbascio, Caterina, Parise, Vincenzo Fricchione, Gardellin, Francesco, Gennaro, Daniele, Hanife, Batul, Lintas, Camilla, Lorusso, Marina, Luca, Antonina, Luca, Maria, Luchetta, Chiara, Lucii, Claudio, Maio, Francesca, Marsilio, Alessandra, Mattei, Chiara, Moretti, Daniele, Nosè, Michela, Occhionero, Guglielmo, Papanti, Duccio, Pecile, Damiano, Percudani, Mauro, Prestia, Davide, Purgato, Marianna, Restaino, Francesco, Romeo, Salvatore, Sciarma, Tiziana, Strizzolo, Stefania, Tamborini, Stefania, Todarello, Orlando, Tozzi, Fiorella, Ziero, Simona, Zotos, Spyridon, Barbui, Corrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210495/
https://www.ncbi.nlm.nih.gov/pubmed/25326163
http://dx.doi.org/10.1186/1756-0500-7-731