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Controlled delivery of BID protein fused with TAT peptide sensitizes cancer cells to apoptosis

BACKGROUND: Low cellular level of BID is critical for viability of numerous cancer cells. Sensitization of cells to anticancer agents by BID overexpression from adenovirus or pcDNA vectors is a proposed strategy for cancer therapy; however it does not provide any stringent control of cellular level...

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Detalles Bibliográficos
Autores principales: Orzechowska, Emilia Joanna, Kozlowska, Ewa, Czubaty, Alicja, Kozlowski, Piotr, Staron, Krzysztof, Trzcinska-Danielewicz, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210496/
https://www.ncbi.nlm.nih.gov/pubmed/25326334
http://dx.doi.org/10.1186/1471-2407-14-771