Genetic mutations in pfcrt and pfmdr1 at the time of artemisinin combination therapy introduction in South Pacific islands of Vanuatu and Solomon Islands

BACKGROUND: Chloroquine (CQ), alone or in combination with sulphadoxine-pyrimethamine, was widely used for the treatment of Plasmodium falciparum and Plasmodium vivax for several decades in both Vanuatu and Solomon Islands prior to the introduction of artemether-lumefantrine (AL) in 2008. However, t...

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Detalles Bibliográficos
Autores principales: Gresty, Karryn J, Gray, Karen-Ann, Bobogare, Albino, Taleo, George, Hii, Jeffrey, Wini, Lyndes, Cheng, Qin, Waters, Norman C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210516/
https://www.ncbi.nlm.nih.gov/pubmed/25318907
http://dx.doi.org/10.1186/1475-2875-13-406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210516/
https://www.ncbi.nlm.nih.gov/pubmed/25318907
http://dx.doi.org/10.1186/1475-2875-13-406

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