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Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression

BACKGROUND: Glucose-regulated proteins (GRP) are induced in the cancer microenvironment to promote tumor survival, metastasis and drug resistance. AST was obtained from the medicinal plant Astragalus membranaceus, which possesses anti-tumor and pro-apoptotic properties in colon cancer cells and tumo...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Auyeung, Kathy K, Zhang, Xiaoyu, Ko, Joshua K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210535/
https://www.ncbi.nlm.nih.gov/pubmed/25319833
http://dx.doi.org/10.1186/1472-6882-14-401