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Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression
BACKGROUND: Glucose-regulated proteins (GRP) are induced in the cancer microenvironment to promote tumor survival, metastasis and drug resistance. AST was obtained from the medicinal plant Astragalus membranaceus, which possesses anti-tumor and pro-apoptotic properties in colon cancer cells and tumo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210535/ https://www.ncbi.nlm.nih.gov/pubmed/25319833 http://dx.doi.org/10.1186/1472-6882-14-401 |