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Enrichment of statistical power for genome-wide association studies

BACKGROUND: The inheritance of most human diseases and agriculturally important traits is controlled by many genes with small effects. Identifying these genes, while simultaneously controlling false positives, is challenging. Among available statistical methods, the mixed linear model (MLM) has been...

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Detalles Bibliográficos
Autores principales: Li, Meng, Liu, Xiaolei, Bradbury, Peter, Yu, Jianming, Zhang, Yuan-Ming, Todhunter, Rory J, Buckler, Edward S, Zhang, Zhiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210555/
https://www.ncbi.nlm.nih.gov/pubmed/25322753
http://dx.doi.org/10.1186/s12915-014-0073-5