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Embelin inhibits TNF-α converting enzyme and cancer cell metastasis: molecular dynamics and experimental evidence

BACKGROUND: Embelin, a quinone derivative, is found in the fruits of Embelia ribes Burm (Myrsinaceae). It has been shown to have a variety of therapeutic potentials including anthelmintic, anti-tumor, anti-diabetic, anti-bacterial and anti-inflammation. Inflammation is an immunological response to e...

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Detalles Bibliográficos
Autores principales: Dhanjal, Jaspreet Kaur, Nigam, Nupur, Sharma, Sudhanshu, Chaudhary, Anupama, Kaul, Sunil C, Grover, Abhinav, Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210574/
https://www.ncbi.nlm.nih.gov/pubmed/25336399
http://dx.doi.org/10.1186/1471-2407-14-775