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SummonChimera infers integrated viral genomes with nucleotide precision from NGS data

BACKGROUND: Viral integration into a host genome is defined by two chimeric junctions that join viral and host DNA. Recently, computational tools have been developed that utilize NGS data to detect chimeric junctions. These methods identify individual viral-host junctions but do not associate chimer...

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Detalles Bibliográficos
Autores principales: Katz, Joshua P, Pipas, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210586/
https://www.ncbi.nlm.nih.gov/pubmed/25331652
http://dx.doi.org/10.1186/s12859-014-0348-4