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The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions

Barrier characteristics of brain endothelial cells forming the blood–brain barrier (BBB) are tightly regulated by cellular and acellular components of the neurovascular unit. During embryogenesis, the accumulation of the heparan sulfate proteoglycan agrin in the basement membranes ensheathing brain...

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Detalles Bibliográficos
Autores principales: Steiner, Esther, Enzmann, Gaby U., Lyck, Ruth, Lin, Shuo, Rüegg, Markus A., Kröger, Stephan, Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210653/
https://www.ncbi.nlm.nih.gov/pubmed/25107608
http://dx.doi.org/10.1007/s00441-014-1969-7