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Delivery of circulating lipoproteins to specific neurons in the Drosophila brain regulates systemic insulin signaling

The Insulin signaling pathway couples growth, development and lifespan to nutritional conditions. Here, we demonstrate a function for the Drosophila lipoprotein LTP in conveying information about dietary lipid composition to the brain to regulate Insulin signaling. When yeast lipids are present in t...

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Detalles Bibliográficos
Autores principales: Brankatschk, Marko, Dunst, Sebastian, Nemetschke, Linda, Eaton, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210815/
https://www.ncbi.nlm.nih.gov/pubmed/25275323
http://dx.doi.org/10.7554/eLife.02862