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Kinetic competition during the transcription cycle results in stochastic RNA processing
Synthesis of mRNA in eukaryotes involves the coordinated action of many enzymatic processes, including initiation, elongation, splicing, and cleavage. Kinetic competition between these processes has been proposed to determine RNA fate, yet such coupling has never been observed in vivo on single tran...
Autores principales: | Coulon, Antoine, Ferguson, Matthew L, de Turris, Valeria, Palangat, Murali, Chow, Carson C, Larson, Daniel R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210818/ https://www.ncbi.nlm.nih.gov/pubmed/25271374 http://dx.doi.org/10.7554/eLife.03939 |
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