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Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl(4)-) Induced Liver Injury in Mice

This study investigated the anti-inflammatory effects of DEC on the CCl(4)-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p. administration of CCl(4) 0.5 μL/g of body weight through two injections a week for 6 weeks. DEC (50 mg/kg) was administered by gavage for 12 day...

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Detalles Bibliográficos
Autores principales: Rocha, Sura Wanessa Santos, de França, Maria Eduarda Rocha, Rodrigues, Gabriel Barros, Barbosa, Karla Patrícia Sousa, Nunes, Ana Karolina Santana, Pastor, André Filipe, Oliveira, Anne Gabrielle Vasconcelos, Oliveira, Wilma Helena, Luna, Rayana Leal Almeida, Peixoto, Christina Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211150/
https://www.ncbi.nlm.nih.gov/pubmed/25374445
http://dx.doi.org/10.1155/2014/696383