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Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl(4)-) Induced Liver Injury in Mice
This study investigated the anti-inflammatory effects of DEC on the CCl(4)-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p. administration of CCl(4) 0.5 μL/g of body weight through two injections a week for 6 weeks. DEC (50 mg/kg) was administered by gavage for 12 day...
Autores principales: | Rocha, Sura Wanessa Santos, de França, Maria Eduarda Rocha, Rodrigues, Gabriel Barros, Barbosa, Karla Patrícia Sousa, Nunes, Ana Karolina Santana, Pastor, André Filipe, Oliveira, Anne Gabrielle Vasconcelos, Oliveira, Wilma Helena, Luna, Rayana Leal Almeida, Peixoto, Christina Alves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211150/ https://www.ncbi.nlm.nih.gov/pubmed/25374445 http://dx.doi.org/10.1155/2014/696383 |
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