Flutamide-Induced Cytotoxicity and Oxidative Stress in an In Vitro Rat Hepatocyte System

Flutamide (FLU) is a competitive antagonist of the androgen receptor which has been reported to induce severe liver injury in some patients. Several experimental models suggested that an episode of inflammation during drug treatment predisposes animals to tissue injury. The molecular cytotoxic mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Maruf, Abdullah Al, O'Brien, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211152/
https://www.ncbi.nlm.nih.gov/pubmed/25371773
http://dx.doi.org/10.1155/2014/398285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211152/
https://www.ncbi.nlm.nih.gov/pubmed/25371773
http://dx.doi.org/10.1155/2014/398285

Ejemplares similares