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Flutamide-Induced Cytotoxicity and Oxidative Stress in an In Vitro Rat Hepatocyte System
Flutamide (FLU) is a competitive antagonist of the androgen receptor which has been reported to induce severe liver injury in some patients. Several experimental models suggested that an episode of inflammation during drug treatment predisposes animals to tissue injury. The molecular cytotoxic mecha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211152/ https://www.ncbi.nlm.nih.gov/pubmed/25371773 http://dx.doi.org/10.1155/2014/398285 |