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A(3) Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action

The A(3) adenosine receptor (A(3)AR) is overexpressed in inflammatory cells and in the peripheral blood mononuclear cells of individuals with inflammatory conditions. Agonists to the A(3)AR are known to induce specific anti-inflammatory effects upon chronic treatment. LUF6000 is an allosteric compou...

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Detalles Bibliográficos
Autores principales: Cohen, Shira, Barer, Faina, Bar-Yehuda, Sara, IJzerman, Adriaan P., Jacobson, Kenneth A., Fishman, Pnina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211160/
https://www.ncbi.nlm.nih.gov/pubmed/25374446
http://dx.doi.org/10.1155/2014/708746