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A Critical Role for Immune System Response in Mediating Anti-influenza Drug Synergies Assessed by Mechanistic Modeling

Influenza virus infections represent a serious public health problem worldwide, due to the rapid emergence of drug resistance. One strategy to improve treatment efficacy is to combine drugs that act synergistically. Potentially useful drug combinations are typically identified through empirical test...

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Detalles Bibliográficos
Autores principales: Li, Z, Zhou, H, Lu, Y, Colatsky, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211263/
https://www.ncbi.nlm.nih.gov/pubmed/25207611
http://dx.doi.org/10.1038/psp.2014.32