Ultralow concentrations of bupivacaine exert anti-inflammatory effects on inflammation-reactive astrocytes

Bupivacaine is a widely used, local anesthetic agent that blocks voltage-gated Na(+) channels when used for neuro-axial blockades. Much lower concentrations of bupivacaine than in normal clinical use, < 10(−8) m, evoked Ca(2+) transients in astrocytes from rat cerebral cortex, that were inositol...

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Detalles Bibliográficos
Autores principales: Block, Linda, Jörneberg, Per, Björklund, Ulrika, Westerlund, Anna, Biber, Björn, Hansson, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Disorders of the Nervous System
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211363/
https://www.ncbi.nlm.nih.gov/pubmed/24083665
http://dx.doi.org/10.1111/ejn.12364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211363/
https://www.ncbi.nlm.nih.gov/pubmed/24083665
http://dx.doi.org/10.1111/ejn.12364

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