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Haptoglobin, hemopexin, and related defense pathways—basic science, clinical perspectives, and drug development

Hemolysis, which occurs in many disease states, can trigger a diverse pathophysiologic cascade that is related to the specific biochemical activities of free Hb and its porphyrin component heme. Normal erythropoiesis and concomitant removal of senescent red blood cells (RBC) from the circulation occ...

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Detalles Bibliográficos
Autores principales: Schaer, Dominik J., Vinchi, Francesca, Ingoglia, Giada, Tolosano, Emanuela, Buehler, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211382/
https://www.ncbi.nlm.nih.gov/pubmed/25389409
http://dx.doi.org/10.3389/fphys.2014.00415