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Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes

Background: Rupture of advanced atherosclerotic plaques accounts for most life-threatening myocardial infarctions. Classical (M1) and alternative (M2) macrophage activation could promote atherosclerotic plaque progression and rupture by increasing production of proteases, including matrix metallopro...

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Detalles Bibliográficos
Autores principales: Hayes, Elaine Mo, Tsaousi, Aikaterini, Di Gregoli, Karina, Jenkinson, S. Rhiannon, Bond, Andrew R., Johnson, Jason L., Bevan, Laura, Thomas, Anita C., Newby, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211548/
https://www.ncbi.nlm.nih.gov/pubmed/25389425
http://dx.doi.org/10.3389/fimmu.2014.00537