The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

UDP-glucuronosyltransferases (UGTs) form a multigenic family of membrane-bound enzymes expressed in various tissues, including brain. They catalyze the formation of β-D-glucuronides from structurally unrelated substances (drugs, other xenobiotics, as well as endogenous compounds) by the linkage of g...

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Detalles Bibliográficos
Autores principales: Ouzzine, Mohamed, Gulberti, Sandrine, Ramalanjaona, Nick, Magdalou, Jacques, Fournel-Gigleux, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211562/
https://www.ncbi.nlm.nih.gov/pubmed/25389387
http://dx.doi.org/10.3389/fncel.2014.00349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211562/
https://www.ncbi.nlm.nih.gov/pubmed/25389387
http://dx.doi.org/10.3389/fncel.2014.00349

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