Inhaled Lactonase Reduces Pseudomonas aeruginosa Quorum Sensing and Mortality in Rat Pneumonia

RATIONALE: The effectiveness of antibiotic molecules in treating Pseudomonas aeruginosa pneumonia is reduced as a result of the dissemination of bacterial resistance. The existence of bacterial communication systems, such as quorum sensing, has provided new opportunities of treatment. Lactonases eff...

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Detalles Bibliográficos
Autores principales: Hraiech, Sami, Hiblot, Julien, Lafleur, John, Lepidi, Hubert, Papazian, Laurent, Rolain, Jean-Marc, Raoult, Didier, Elias, Mikael, Silby, Mark W., Bzdrenga, Janek, Bregeon, Fabienne, Chabriere, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211673/
https://www.ncbi.nlm.nih.gov/pubmed/25350373
http://dx.doi.org/10.1371/journal.pone.0107125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211673/
https://www.ncbi.nlm.nih.gov/pubmed/25350373
http://dx.doi.org/10.1371/journal.pone.0107125

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