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Longevity and Plasticity of CFTR Provide an Argument for Noncanonical SNP Organization in Hominid DNA

Like many other ancient genes, the cystic fibrosis transmembrane conductance regulator (CFTR) has survived for hundreds of millions of years. In this report, we consider whether such prodigious longevity of an individual gene – as opposed to an entire genome or species – should be considered surpris...

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Detalles Bibliográficos
Autores principales: Hill, Aubrey E., Plyler, Zackery E., Tiwari, Hemant, Patki, Amit, Tully, Joel P., McAtee, Christopher W., Moseley, Leah A., Sorscher, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211684/
https://www.ncbi.nlm.nih.gov/pubmed/25350658
http://dx.doi.org/10.1371/journal.pone.0109186