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The Functions of Crucial Cysteine Residues in the Arsenite Methylation Catalyzed by Recombinant Human Arsenic (III) Methyltransferase

Arsenic (III) methyltransferase (AS3MT) is a cysteine (Cys)-rich enzyme that catalyzes the biomethylation of arsenic. To investigate how these crucial Cys residues promote catalysis, we used matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) to analyze Cys re...

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Detalles Bibliográficos
Autores principales: Wang, Shuping, Geng, Zhirong, Shi, Nan, Li, Xiangli, Wang, Zhilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211708/
https://www.ncbi.nlm.nih.gov/pubmed/25349987
http://dx.doi.org/10.1371/journal.pone.0110924